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目的:评价丹红注射液治疗不稳定型心绞痛(UAP)合并高脂血症患者的有效性、安全性及对高血脂指标的影响。方法:将78例UAP合并高脂血症患者随机分成治疗组(丹红)35例和对照组43例,两组同时常规应用鲁南欣康、阿司匹林、低分子肝素钙等治疗。比较两组在治疗前后心绞痛疗效、血脂指标的变化,同时观察药物过敏等副作用。结果:治疗组与对照组相比,能显著改善UAP的症状及缺血性心电图表现(P<0.05),治疗组总胆固醇、甘油三酯、低密度脂蛋白的指标下降幅度均优于对照组(P<0.05)。结论:丹红注射液对UAP的治疗及对高血脂指标的改善是安全和有效的。
Objective: To evaluate the effectiveness and safety of Danhong injection in patients with unstable angina pectoris (UAP) complicated with hyperlipidemia and its effect on hyperlipidemia. Methods: A total of 78 UAP patients with hyperlipidemia were randomly divided into treatment group (Danhong) 35 cases and control group 43 cases. Both groups were treated with Lunanxinkang, aspirin and low molecular weight heparin calcium at the same time. The curative effect of angina pectoris and the change of blood lipid index were compared between the two groups before and after treatment, and side effects such as drug allergy were also observed. Results: Compared with the control group, the treatment group could significantly improve the symptoms of UAP and the manifestation of ischemic electrocardiogram (P <0.05). The decrease of total cholesterol, triglyceride and low density lipoprotein in the treatment group was better than that in the control group (P <0.05). Conclusion: Danhong injection for UAP treatment and improvement of hyperlipidemia indicators is safe and effective.