柳氮磺胺吡啶(sulfasalazine)临床用于溃疡性结肠炎和旅行者腹泻的治疗。本品经肠细菌酶分解释放出5-氨基水杨酸和磺胺吡啶。近来认为本品的局部抗炎作用与5-氨基水杨酸抑制前列腺素的合成有关。最近国外临床评价认为柳氮磺胺吡啶是一种有效的治疗类风湿关节炎的缓解药。 Sulfasalazine is clinically used in the treatment of ulcerative colitis and traveler’s diarrhea. This product is decomposed by intestinal bacterial enzymes to release 5-aminosalicylic acid and sulfapyridine. Recently that the local anti-inflammatory effect of this product and 5-aminosalicylic acid inhibition of prostaglandin synthesis. Recent foreign clinical evaluation that sulfasalazine is an effective anti-rheumatoid arthritis treatment of drugs.