波前像差严重影响了人眼正常的视觉质量,引入Hartm ann-Shack波前传感器可有效地测量人眼的各阶像差,结合自适应光学中Zern ike多项式重建波前的理论。建立人眼波前像差和角膜切削量模型的关系模型,利用准分子激光发射的激光脉冲去除定量的角膜组织,从而改善人眼视觉质量。应用表明,人眼像差测量和由像差引导的准分子激光手术矫正具有明显的临床医学价值。 The wavefront aberration seriously affects the normal visual quality of the human eye. The introduction of the Hartm ann-Shack wavefront sensor can effectively measure the human eye aberrations, combined with the theory of Zernike polynomials in adaptive optics to reconstruct the wavefront. The relationship model of human wavefront aberration and corneal ablation volume was established, and quantitative corneal tissue was removed by using laser pulses emitted by excimer laser to improve the visual quality of human eyes. Application shows that the human eye aberration measurement and aberration-guided excimer laser surgery has obvious clinical value.