论文部分内容阅读
目的 :研究肉苁蓉总苷 (glycosidesofcistanche ,GC)对家兔失血性休克 /再灌注 (hemorrhagicshock/reperfusion ,S/R)损伤的治疗作用。方法 :应用家兔S/R模型 ,观察血浆中过氧化脂质 (LPO)含量、丙二醛 (MDA)含量、超氧化物歧化酶(SOD)活性和血栓素A2 (TXA2 )、前列环素 (PGI2 )代谢产物的浓度以及GC对上述指标的影响。结果 :与假手术组比较 ,S/R组LPO、MDA、TXB2 明显升高 ,SOD、6-酮 -PGF1α明显降低 ,GC可逆转上述指标的变化。结论 :GC对S/R损伤有治疗作用。
Objective: To study the therapeutic effect of glycosides of cistanche (GC) on hemorrhagic shock / reperfusion injury in rabbits. Methods: Rabbit S / R model was used to observe the contents of lipid peroxidation (LPO), malondialdehyde (MDA), superoxide dismutase (SOD) and thromboxane A2 (TXA2), prostacyclin (PGI2) metabolites concentration and GC on the above indicators. Results: Compared with sham operation group, LPO, MDA and TXB2 in S / R group were significantly increased, while SOD and 6-keto-PGF1α were significantly decreased. GC could reverse the above indexes. Conclusion: GC has a therapeutic effect on S / R injury.