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在微生物的生长过程中,若受到某些生物活性物质的影响,其菌丝体或分生孢子就会产生形态学上的变异,如卷曲-膨胀-分散过度-形成串珠状或菌丝体生长受阻。Kobayashi等曾利用这种现象开发了一种新的方法,用以筛选抗真菌和抗肿瘤的物质。用一种致植物病的真菌PyriculariaoryzaeP-26
During the growth of microorganisms, mycelia or conidia may undergo morphological variations such as curl-expansion-overdispersion-beading or mycelial growth if they are affected by certain biologically active substances. Blocked. Kobayashi et al. used this phenomenon to develop a new method for screening antifungal and antitumor substances. With a phytopathogenic fungus Pyricularia oryzae P-26