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目的了解江苏省孕妇弓形虫感染情况。方法 2009-2010年选择全省7个市的孕妇作为调查对象,采用酶联免疫吸附试验检测抗弓形虫特异性抗体IgM、IgG。按照《江苏省弓形虫病个案调查表》统一录取信息进行统计分析。结果 1081名孕妇弓形虫IgM均为阴性,IgG阳性率为3.98%(43/1 081),与对照组的2.27%(4/176)差异无统计学意义(χ2=1.23,P>0.05);各市间阳性率差异无统计学意义(χ2=2.07,P>0.05)。IgG阳性率早孕组为3.78%,中晚孕组为4.17%,与对照组3组间差异无统计学意义(χ2=1.33,P>0.05)。既往有病理性流产史的孕妇无弓形虫IgG阳性者。仅1.84%(8/435)的孕妇曾做过弓形虫相关检测。结论江苏省孕妇弓形虫感染率处于较低状态,地区间差异不大;应积极开展围孕期弓形虫检测,根据不同对象采取相应的防治对策;同时需进一步在居民中开展加强弓形虫病防治知识的健康教育。
Objective To understand the infection of toxoplasma in pregnant women in Jiangsu province. Methods From 2009 to 2010, pregnant women from 7 cities in the province were selected as the research objects. Anti-Toxoplasma gondii-specific IgM and IgG were detected by enzyme-linked immunosorbent assay (ELISA). In accordance with the “Jiangsu province toxoplasmosis case questionnaire” uniform admission information for statistical analysis. Results The IgM of 1081 pregnant women was negative, the positive rate of IgG was 3.98% (43/1 081), which was not significantly different from that of the control group (2.27%, 4/176) (χ2 = 1.23, P> 0.05). There was no significant difference in the positive rate among the cities (χ2 = 2.07, P> 0.05). The positive rate of IgG was 3.78% in the early pregnancy group and 4.17% in the middle and late pregnancy group, there was no significant difference between the three groups (χ2 = 1.33, P> 0.05). Past history of pathological abortion in pregnant women without Toxoplasma gondii IgG positive. Only 1.84% (8/435) of pregnant women had done Toxoplasma related testing. Conclusion The infection rate of Toxoplasma gondii in pregnant women in Jiangsu Province is in a low state, with no significant difference among regions. Toxoplasma gondii detection should be carried out during pregnancy and corresponding prevention and treatment measures should be taken according to different targets. At the same time, it is necessary to further strengthen the prevention and control of Toxoplasmosis among residents Health education.