Sjogren's综合征(简称SS)是一种以口腔干燥症、干燥性角、结膜炎和胶原病为特征的慢性全身性自身免疫性疾病。原发患者有干燥症状,伴发于胶原病者称为继发性SS。胶原病多为类风湿性关节炎、系统性红斑狼疮、硬皮病、多发性结节性动脉炎等,还可有其他外分泌腺的表现,如甲状腺炎、间质性肾炎 Sjogren's syndrome (SS) is a chronic systemic autoimmune disease characterized by xerostomia, dry angle, conjunctivitis and collagen disease. Primary patients have dry symptoms, associated with collagen disease known as secondary SS. Collagen disease mostly rheumatoid arthritis, systemic lupus erythematosus, scleroderma, multiple nodular arteritis, but also have other exocrine manifestations, such as thyroiditis, interstitial nephritis