据认为产青霉素酶淋球菌(PPNG)菌株起源于东南亚和非洲,尽管这两个地理上不同的地区的 PPNG 菌株彼此有关,但也表现出具有不同的性质。来自东南亚的 PPNG 菌株携带4.4×10~6道尔顿青霉素酶编码的质粒(常与24.5×10~6道尔顿质粒结合),系原养型菌株或需要脯氨酸生长,对抗生素有适度的抗药性。相反,来自非洲的 PPNG 菌株携带3.2×10~6道尔顿青霉素酶编码的质粒, It is believed that strains of penicillinase-producing Neisseria gonorrhoeae (PPNG) originated in South-East Asia and Africa and although the PPNG strains of these two geographically distinct regions are related to each other, they also exhibit different properties. PPNG strains from Southeast Asia carry 4.4 × 10 ~ 6 Dalton penicillinase-encoding plasmid (often with 24.5 × 10 ~ 6 Dalton plasmid), Department of prototrophic strains or need proline growth, moderate antibiotics Resistance. In contrast, the PPNG strain from Africa carries a 3.2 × 10 -6 Daltonian penicillinase-encoding plasmid,