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5. Genetic factors for individual administration of immunosuppressants in organ transplantation

Genetic factors for individual administration of immunosuppressants in organ transplantation

来源 :国际肝胆胰疾病杂志：英文版 | 被引量 : 0次 | 上传用户：yzahnig621

【摘 要】

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【正】BACKGROUND: The immunosuppressive drugs used worldwide have a narrow therapeutic index, which results in a need to individualize the dose regimen for diff

【出 处】

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国际肝胆胰疾病杂志：英文版

【发表日期】

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2006年3期

【关键词】

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CYTOCHROME P4503A P-GLYCOPROTEIN PHARMACOGENETICS INDIVIDUAL ADMINISTRATION cyto 

【基金项目】

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This study was supported by a grant from the 973 National Basic Research Program of China (2003CB515501)

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【正】BACKGROUND: The immunosuppressive drugs used worldwide have a narrow therapeutic index, which results in a need to individualize the dose regimen for different recipients. The oxidative enzymes cytochrome P450 (CYP)3A and the drug efflux pump P-glycopr

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