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对照观察了密骨片和尼尔雌醇对绝经后骨质疏松症的临床疗效。结果显示：密骨片治疗６个月后，全身骨痛及腰背酸痛等症状与体征有明显改善，与尼尔雌醇比较有显著性的差异（Ｐ＜０．０５）；其尺、桡骨骨矿物质含量较治疗前明显增加（Ｐ＜０．０５），但尼尔雌醇组与治疗前相比无明显差异（Ｐ＞０．０５）；血清碱性磷酸酶、血清钙、血清磷含量治疗前后无明显差异（Ｐ＞０．０５）；空腹尿钙／尿肌酐两组均明显下降（Ｐ＜０．０５）。提示：密骨片不仅能降低妇女绝经后代谢性骨质丢失，还可在一定程度上促进骨的形成。
The clinical effects of Tiegu tablets and Nilestriol on postmenopausal osteoporosis were observed. The results showed that after 6 months of treatment with Migu tablets, the symptoms and signs of systemic bone pain and low back pain were significantly improved, which was significantly different from that of nilestriol (P<0.05); The bone mineral content was significantly increased (P<0.05) before treatment, but there was no significant difference between the Nylestriol group and the pretreatment (P>0.05); serum alkaline phosphatase, serum calcium, serum phosphorus There was no significant difference before and after treatment (P>0.05); fasting urinary calcium/urine creatinine decreased significantly in both groups (P<0.05). Tip: TMD can not only reduce metabolic bone loss in postmenopausal women, but also promote bone formation to a certain extent.