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目的探讨亚甲蓝前哨淋巴结活检(SLNB)在基层医院早期低危乳腺癌手术中的应用方法及效果。方法对32例入选乳腺癌患者行美蓝染色法检测前哨淋巴结(SLN),并对其中5例SLN阳性者行腋窝淋巴结清扫术(ALND)。结果 32例患者中31例检出SLN,检出率为96.9%(31/32),共检出SLN 50个,其中1个SLN者17例,2个SLN者10例,3个SLN者3例,4个SLN者1例。对术中病理切片检查结果提示SLN阳性者5例行ALND;其余SLN阴性的27例者则避免了ALND。结论对于早期乳腺癌常规应用美蓝SLNB是一种简单、经济且有效的方法,可使早期低危乳腺癌患者发生ALND相关并发症的危险性降低。
Objective To investigate the method and effect of methylene blue sentinel lymph node biopsy (SLNB) in primary low-risk breast cancer surgery in primary hospitals. Methods Sentinel lymph nodes (SLNs) were detected by methylene blue staining in 32 patients with breast cancer, and axillary lymph node dissection (ALND) was performed on 5 SLN positive patients. Results Of the 32 cases, SLN was detected in 31 cases and the detection rate was 96.9% (31/32). A total of 50 SLNs were detected. Among them, 1 case had SLN in 17 cases, 2 cases had SLN in 10 cases and 3 cases had SLN in 3 cases Cases, 4 SLN in 1 case. The results of intraoperative pathological examination showed that 5 patients with SLN-positive ALND; the other 27 patients with negative SLN were to avoid ALND. Conclusion The routine application of methylene blue SLNB for early breast cancer is a simple, economical and effective method to reduce the risk of ALND-related complications in early-stage low-risk breast cancer patients.