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目的探讨阿糖腺苷联合痰热清治疗小儿病毒性脑炎的临床疗效。方法将武陟县人民医院2007年10月-2010年10月收治的92例病毒性脑炎患儿随机分为两组,对照组46例采用吸氧、镇静、解痉、退热、降颅内压、应用营养脑神经药物、维持水电解质及酸碱平衡、营养支持等常规综合治疗,治疗组46例在常规治疗的基础上给予阿糖腺苷联合痰热清治疗,两组疗程均为7~14 d。结果治疗组的总有效率明显高于对照组,两组比较差异有统计学意义(P<0.05);治疗组的退热时间、头痛呕吐消失时间、抽搐消失时间、意识恢复时间及住院天数均明显短于对照组,两组相比较差异也有统计学意义(P<0.05)。结论阿糖腺苷联合痰热清治疗小儿病毒性脑炎的疗效确切,能快速改善临床症状,缩短病程,且不良反应少,值得临床借鉴。
Objective To investigate the clinical efficacy of adenosine triphosphate combined with Tanreqing in treating children with viral encephalitis. Methods Ninety-two children with viral encephalitis admitted to Wudai County People’s Hospital from October 2007 to October 2010 were randomly divided into two groups. In the control group, 46 patients were treated with oxygen inhalation, sedation, antispasmodic, antipyretic, Internal pressure, the application of nutrition brain nerve drugs, to maintain water and electrolyte and acid-base balance, nutritional support and other conventional comprehensive treatment, the treatment group of 46 patients on the basis of conventional treatment given adenosine combined with phlegm heat treatment, the two groups were 7 ~ 14 d. Results The total effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant (P <0.05); the treatment group’s antipyretic time, disappearance of headache and vomiting, disappearance of convulsions, consciousness recovery time and hospitalization days Obviously shorter than the control group, the difference between the two groups was also statistically significant (P <0.05). Conclusions The combination of adenosine triphosphate and Tanreqing is effective in treating viral encephalitis in children, which can rapidly improve the clinical symptoms and shorten the course of the disease, with less adverse reactions, which is worthy of clinical reference.