血清中miRNA作为肿瘤标记物的研究进展

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microRNA(miRNA)是一种大小为22nt左右的单链RNA,主要功能是调节基因的表达.它在组织和血清中都存在,并在血清中具有很好的稳定性.一些血清中miRNA已被证实在癌症患者中特异性异常表达.血清中miRNA有着高度的稳定性、敏感性和特异性,因此其有望作为一种基于血清检测癌症的新标记物.
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