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本文报告应用抗猪囊尾蚴单克隆抗体(McAb)4F8-ELISA 对 231例脑囊虫病患者脑脊液中循环抗原(CAg)检测的结果。经与患者病史、临床分型和脑CT检查结果比较,发现脑脊液中CAg 与有无绦虫史无关。脑型合并皮下结节患者脑脊液中CAg 的阳性率明显高于单纯型脑囊虫病和皮下结节消失组的患者。CAg 检测的结果与囊尾蚴在脑部寄生的数量,病灶的新旧与部位等病理情况有关。表明 McAb(4F8)-ELISA 不仅可用于脑囊虫病的诊断,也有可能用于疗效评价。
This article reports the results of detection of cerebrospinal fluid circulating antigen (CAg) in 231 patients with cysticercosis using McAbs against Cysticercus cellulosae (McAb) 4F8-ELISA. After comparing with patient’s history, clinical classification and brain CT examination results, it was found that cerebrospinal fluid CAg has no correlation with the history of the presence or absence of tapeworm. The positive rate of CAg in cerebrospinal fluid in patients with cerebral combined subcutaneous nodules was significantly higher than that in patients with simple cysticercosis and subcutaneous nodules disappeared. CAg test results and the number of cysticerci in the brain parasites, lesions of the old and the new parts and other pathological conditions. McAb (4F8) -ELISA is not only used for the diagnosis of cerebral cysticercosis, but also for the evaluation of the curative effect.