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目的:探讨快速康复外科理念对结直肠癌腹腔镜根治术患者术后康复、免疫功能及营养状态影响。方法:选择绍兴文理学院附属医院于2017年6月至2019年6月收治的结直肠癌腹腔镜根治术患者106例,依据随机数字表法分为观察组与对照组,每组53例。观察组采用快速康复外科理念,对照组采用常规康复外科理念。比较两组术中出血量、术后并发症和手术时间,术后胃肠功能康复,术前1 d和术后3 d免疫功能和营养指标变化。结果:两组术中出血量和手术时间差异均无统计学意义(均n P>0.05);观察组术后并发症发生率为5.66%(3/53),低于对照组的24.53%(13/53),差异有统计学意义(χn 2=7.361,n P<0.05)。观察组肛门首次排气时间[(2.14±0.32)d]和首次进食时间[(1.85±0.42)d]均快于对照组[(3.62±0.61)d和(2.79±0.36)d](n t=15.642、12.371,均n P<0.05)。观察组术后3 d CDn 3+ [(50.82±2.31)%]、CDn 4+ [(34.01±2.19)%]和CDn 4+/CDn 8+ (1.03±0.08)均高于对照组[(46.30±2.68)%、(30.26±2.05)%和(0.81±0.12)](n t=9.300、9.101、11.105,均n P<0.05)。观察组术后3 d血清转铁清蛋白[(1.97±0.14)g/L]和前清蛋白[(0.23±0.03)g/L]均高于对照组[(1.72±0.15)g/L和(0.18±0.03)g/L](n t=8.870、8.580,均n P0.05). The incidence of postoperative complications in the observation group was 5.66%(3/53), which was lower than 24.53%(13/53) in the control group(χn 2=7.361, n P<0.05). The time of first anal exhaust[(2.14±0.32)d] and first eating[(1.85±0.42)d]in the observation group were shorter than those in the control group[(3.62±0.61)d and (2.79±0.36)d](n t=15.642, 12.371, all n P<0.05). Three days after operation, the CDn 3+ [(50.82±2.31)%], CDn 4+ [(34.01±2.19)%]and CDn 4+/CDn 8+ (1.03±0.08) in the observation group were higher than those in the control group[(46.30±2.68)%, (30.26±2.05)% and (0.81±0.12)](n t=9.300, 9.101, 11.105, all n P<0.05). The serum transferrin[(1.97±0.14)g/L]and prealbumin[(0.23±0.03)g/L] in the observation group were higher than those in the control group[(1.72±0.15)g/L and (0.18±0.03)g/L](n t=8.870, 8.580, all n P<0.05).n Conclusion:The surgery concept of rapid rehabilitation can promote the postoperative rehabilitation of patients with colorectal cancer, improve the immune function and nutritional status of patients, and has less complications.