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前列腺素(Prostaglandin,PG)是一类具有广泛生理活性的激素,被誉为七十年代的“甾体激素”。它广泛存在于人和动物的各种组织和体液中,其含量虽微但却具有多种多样强烈的生理作用。如降低血压、收缩子宫、松驰支气管平滑肌、抑制胃酸分泌和血小板凝集等。可用于避孕、治疗高血压、血栓、胃溃疡等疾病。它不仅在药学和临床医学方面具有广阔的前途,而且对生命科学的研究也具有重要的理论意义。前列腺素是于五十年代末从羊精囊中分离得到,其基本骨架为前列酸(Prostanoicacidl),现已发现的前列腺素已达20多种。按照五碳环上的取代情况,将前列腺素分
Prostaglandin (PG) is a class of hormone with a wide range of physiological activity, known as the “steroid hormone” of the seventies. It exists in a wide range of human and animal tissues and body fluids, its content is micro but it has a variety of strong physiological effects. Such as reducing blood pressure, contraction of the uterus, bronchial smooth muscle relaxation, inhibition of gastric acid secretion and platelet aggregation. Can be used for contraception, treatment of hypertension, thrombosis, gastric ulcer and other diseases. It not only has a promising future in pharmacy and clinical medicine, but also has important theoretical significance for the study of life sciences. Prostaglandin is isolated from the sheep seminal vesicle in the late fifties. Its basic skeleton is Prostanoic acid, and more than 20 prostaglandins have been found. In accordance with the replacement of five carbon ring, the prostaglandin points