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目的 :探讨压力控制通气 (PCV)用于治疗创伤性急性呼吸窘迫综合征 (ARDS)的临床应用价值。方法 :观察创伤性 ARDS患者 PCV组和容量控制通气 (VCV)治疗后 6和 12小时气道峰压 (PIP) ,平均气道压(MPaw)和呼气末正压 (PEEP)的大小 ,并比较 PCV治疗对血气、血压和心率的影响。结果 :PCV组治疗后 6和12小时 PIP均显著低于 VCV组 (P均 <0 .0 1) ,6小时 MPaw和 PEEP与 VCV比较无显著差异 (P均 >0 .0 5 ) ,而 12小时 PCV组 MPaw和 PEEP均显著低于 VCV组 (P<0 .0 5和 P<0 .0 1)。 PCV组治疗后血气分析、心率和呼吸显著改善 ,血压无明显变化。结论 :PCV治疗创伤性 ARDS能显著降低 PIP,并不增加 MPaw和PEEP值 ,对血流动力学也无明显影响
Objective: To investigate the clinical value of pressure controlled ventilation (PCV) in the treatment of traumatic acute respiratory distress syndrome (ARDS). Methods: The peak airway pressure (PIP), mean airway pressure (MPaw) and positive end expiratory pressure (PEEP) at 6 and 12 hours after traumatic ARDS were measured in patients with PCV and volume controlled ventilation (VCV) Compare the effects of PCV treatment on blood gas, blood pressure and heart rate. Results: The PIP in PCV group was significantly lower than that in VCV group at 6 and 12 hours after treatment (P <0.01). There was no significant difference in MPaw and PEEP between 6 hours and VCV (P> 0.05) MPh and PEEP in PCV group were significantly lower than those in VCV group (P <0.05 and P <0.01). Blood gas analysis, heart rate and respiration were significantly improved after PCV treatment, with no significant changes in blood pressure. Conclusions: PCV treatment of traumatic ARDS can significantly reduce PIP, does not increase MPaw and PEEP values, and has no significant effect on hemodynamics