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目的:观察瑞芬太尼复合异丙酚用于人工流产手术中的麻醉效果。方法:92例择期行人工流产的早孕患者为研究对象。随机分为单药组和复合组,每组46例患者,单药组静脉滴注异丙酚,复合组静脉滴注异丙酚和瑞芬太尼。比较两组患者异丙酚总用量、诱导时间、意识恢复时间、镇痛效果以及术后综合征。结果:复合组患者的异丙酚总用量、诱导时间和意识恢复时间均少于单药组,差异明显,且有统计学意义(P<0.05)。复合组患者的镇静满意度为100.0%高于单药组87.0%,差异明显,且有统计学意义(P<0.05)。两组患者术后均未见严重的不良反应。两组患者出现不良反应的发生率比较无明显差异,无统计学意义(P>0.05)。结论:瑞芬太尼复合异丙酚用于无痛人流手术,可有效减少异丙酚的用量,并缩短诱导时间和意识恢复时间;且其麻醉效果好、镇痛作用强、安全性高等优点。
Objective: To observe the anesthetic effect of remifentanil and propofol in induced abortion. Methods: 92 cases of early pregnancy induced abortion were studied. Randomly divided into single-drug group and compound group, each group of 46 patients, single-drug group, propofol intravenous infusion of propofol and remifentanil. Total propofol consumption, induction time, recovery time, analgesic effect and postoperative syndrome were compared between the two groups. Results: The total propofol dosage, induction time and consciousness recovery time in the combined group were all less than those in the single drug group, with significant difference (P <0.05). The sedation satisfaction rate was 100.0% in the combination group and 87.0% in the monotherapy group, with significant difference (P <0.05). No serious adverse reactions were found in both groups after operation. There was no significant difference in the incidence of adverse reactions between the two groups, with no statistical significance (P> 0.05). Conclusion: Remifentanil combined with propofol for painless abortion can effectively reduce the dosage of propofol, and shorten the induction time and consciousness recovery time; and its anesthetic effect, analgesic effect, high safety advantages .