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报告超选择性颈内动脉内灌注盐酸嘧啶亚硝脲（ＡＣＮＵ）治疗胶质瘤１６例，病理不明脑肿瘤２例。化疗前及化疗后一月检查ＣＴ比较瘤体积变化。１６例胶质瘤中，１例肿瘤完全消失（完全缓解ＣＲ），５例瘤体缩小大于５０％（部分缓解ＰＲ），５例瘤体缩小小于５０％（无改变ＮＣ），５例瘤体增大（进展ＰＤ）。患者能很好耐受化疗，Ｋａｒｎｏｆｓｋｙ计分在化疗前后几无变化，全身并发症少见而轻微。１例眼动脉下化疗的病人，出现同侧眼部不适、流泪，化疗结束后缓解。未发现神经毒性反应。本文对颈内动脉内化疗的方法、给药剂量及并发症进行探讨。
Report of super selective intra-arterial infusion of pyrimidine hydrochloride nitrile urea (ACNU) in 16 cases of glioma, pathological brain tumor in 2 cases. Before chemotherapy and January after chemotherapy, CT examination of tumor volume changes. Of the 16 gliomas, one completely disappeared (complete remission), 5 had a reduction of more than 50% (partial response PR), 5 had a reduction of less than 50% (no change in NC), 5 had tumors Increase (Progress PD). Patients were well tolerated with chemotherapy, Karnofsky scored almost unchanged before and after chemotherapy, and systemic complications were rare and mild. A case of ophthalmic chemotherapy patients, ipsilateral eye discomfort, tears, chemotherapy after the remission. No neurotoxic reaction was found. In this paper, the method of internal carotid artery chemotherapy, dose and complications were discussed.