水杨酸盐可引起低血糖及代谢性饿中毒,多见于儿童及原有糖尿病或并用其他降糖剂者。本文报告一例78岁的妇女,无糖尿病,因变性性关节炎长期服用阿斯匹林,因用量较大,出现嗜睡、精神错乱、呼吸急促、两肺底有罗音,脉率84次/分、偶有期前收缩及定向力障碍等。化验血中水杨酸盐浓度为60.8m g/d1,已达中毒水平;血糖38mg/d1;动脉PH7.28;血气为代谢性酸中毒伴呼吸性硷中毒。患者应用50％葡萄糖 Salicylate can cause hypoglycemia and metabolic starvation, more common in children and the original diabetes or other hypoglycemic agents. This article reports a 78-year-old woman, long-term aspirin without diabetes, degenerative arthritis, due to greater consumption, drowsiness, confusion, shortness of breath, rales at the bottom of both lungs, pulse rate 84 beats / min , Occasional premature contractions and disability and other obstacles. Laboratory blood salicylate concentration of 60.8m g / d1, has reached the level of poisoning; blood glucose 38mg / d1; arterial PH7.28; blood gas for metabolic acidosis with respiratory alkalosis. Patients apply 50% glucose