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为了解本地区戊型肝炎(HE)流行特征及危险因素,于1994年3~12月对385例急性散发性病毒性肝炎进行血清学分型。结果:甲型肝炎191例(49.61%),乙型肝炎104例(27.01%),丙型肝炎20例(5.19%),HE34例(8.80%),未能分型22例(5.72%)。HE男∶女为6.5∶1,发病平均年龄38.5岁;临床特点:起病急,病程短,预后好;3例HE孕妇中,1例发生死胎。将1993~1994年确诊的70例HE病人作病例组,按性别年龄配比选70例非肝炎病人作对照,进行配比病例对照研究,经单因素和多因素条件logistic回归分析表明:在外用餐史(OR2.01,95%CL1.28~3.15),肝炎接触史(OR6.04,95%CL1.24~29.29),不洁饮食史(OR2.16,95%CL2.05~2.26),3个因素为本病的主要危险因素。
To understand the epidemiological characteristics and risk factors of hepatitis E (HE) in the region, 385 cases of acute sporadic viral hepatitis were serotyped from March to December 1994. Results: 191 cases of hepatitis A (49.61%), 104 cases of hepatitis B (27.01%), 20 cases of hepatitis C (5.19%) and 34 cases of HE (8.80% Type 22 cases (5.72%). HE male: female 6.5: 1, the average age of onset of 38.5 years old; clinical features: acute onset, short course, good prognosis; 3 cases of HE pregnant women, 1 case of stillbirth. 70 cases of HE patients diagnosed from 1993 to 1994 were selected as the case group and 70 cases of non-hepatitis patients were selected as the control by sex age-matched to carry out comparative case-control study. The single-factor and multi-factor conditional logistic regression analysis showed that: (OR2.01,95% CL1.28 ~ 3.15), hepatitis history (OR6.04,95% CL1.24-29.29), unclean diet history (OR2.16,95% CL2.05 ~ 2.26), three factors are the main risk factors for this disease.