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目的观察补肾中药联合抗淋巴细胞球蛋白或腺细胞球蛋白治疗重型再生障碍性贫血患者的临床疗效。方法将42例重型再生障碍性贫血患者随机均分为两组。对照组使用抗淋巴细胞球蛋白或腺细胞球蛋白治疗;治疗组在对照组治疗基础上加用补肾中药。结果治疗组总有效率高于对照组(P<0.05),网织红细胞、血红蛋白、血小板、中性粒细胞水平明显高于对照组(P<0.05);两组不良反应差异经统计学分析有统计学意义(P<0.05)。结论补肾中药联合抗淋巴细胞球蛋白或腺细胞球蛋白对重型再生障碍性贫血患者的临床效果好,外周血象恢复快,值得临床合理选用。
Objective To observe the clinical efficacy of Bushen Chinese medicine combined with anti-lymphocyte globulin or gland globulin in patients with severe aplastic anemia. Methods A total of 42 patients with severe aplastic anemia were randomly divided into two groups. Control group using anti-lymphocyte globulin or gland globulin treatment; treatment group in the control group based on the treatment of kidney with traditional Chinese medicine. Results The total effective rate in the treatment group was higher than that in the control group (P <0.05). The reticulocyte, hemoglobin, platelet and neutrophil levels in the treatment group were significantly higher than those in the control group (P <0.05). The differences in adverse reactions between the two groups were statistically analyzed Statistical significance (P <0.05). Conclusion Bushen Chinese medicine combined with anti-lymphocyte globulin or gland globulin in patients with severe aplastic anemia clinical effect is good, fast recovery of peripheral blood, it is clinically rational selection.