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体内抗环子孢子蛋白抗体的存在,表明曾感染疟原虫,此法能用于流行病学调查,评价一个地区疟疾传播的强度。作者为了评估去非洲撒哈拉以南的西欧旅游者的疟疾感染情况,对1994年1月—1995年9月在该地旅游14—120天(平均58天)、返回德国等地后90天内均无发热症状的222位门诊病人,用合成的NANP_(40)探针ELISA试剂盒观察了抗恶性疟原虫环子孢子抗体的水平。所有患者在旅游期间和旅游返回后4周内均服用
The presence of anti-cyclosporin antibodies in vivo, indicating that they have been infected with Plasmodium, can be used in epidemiological investigations to assess the intensity of malaria transmission in a region. In order to assess malaria infection among Western European tourists traveling to sub-Saharan Africa, the author visited the area between January 1994 and September 1995 for 14-120 days (average 58 days) and returned to Germany within 90 days Of 222 outpatients with fever symptoms, the level of circumsporozoite antibodies against Plasmodium falciparum was observed using a synthetic NANP 40 probe ELISA kit. All patients were taken during the trip and within 4 weeks of the return trip