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目的 :探讨阿莫西林、克拉霉素、雷呗拉唑三联短程疗法治疗胃溃疡的临床效果。方法 :将我院收治的72例胃溃疡患者,随机分为对照组和观察组,对照组采用雷贝拉唑治疗,观察组采用阿莫西林、克拉霉素、雷贝拉唑三联短程疗法治疗,分析两组治疗效果及不良反应发生情况。结果 :治疗后,观察组总有效率97.3%,HP根除率为97.3%;对照组总有效率77.8%,HP根除率为77.8%。两组根治率、总有效率经统计学分析,差异有统计学意义(P<0.01)。结论 :采用阿莫西林、克拉霉素、雷贝拉唑三联疗法治疗胃溃疡,疗效优于雷贝拉唑单独治疗,HP根治率高,不良反应少,使用方便,值得临床推广应用。
Objective: To investigate the clinical effect of amoxicillin, clarithromycin and levualazole triple therapy in the treatment of gastric ulcer. Methods: 72 patients with gastric ulcer admitted to our hospital were randomly divided into control group and observation group. The control group was treated with rabeprazole. The observation group was treated with amoxicillin, clarithromycin and rabeprazole triple short-term therapy , Analysis of the two groups of treatment and adverse reactions occurred. Results: After treatment, the total effective rate was 97.3% in the observation group and 97.3% in the HP group. The total effective rate was 77.8% in the control group and 77.8% in the HP group. The two groups of cure rate, total effective rate by statistical analysis, the difference was statistically significant (P <0.01). Conclusion: The triple therapy of amoxicillin, clarithromycin and rabeprazole is superior to rabeprazole alone in the treatment of gastric ulcer. The cure rate of HP is high, the adverse reactions are few, and it is convenient to use. It is worthy of clinical application.