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目的:探讨血液灌流联合血液透析治疗药物性肝损害的临床效果。方法:选择医院收治的药物性肝损害患者76例,随机分为实验组和对照组,比较两组患者治疗前后胆红素情况及肝功能情况。结果:治疗前,两组患者胆红素、肝功能比较差异无统计学意义(P>0.05);治疗后,实验组患者胆红素,肝功能高于对照组,比较差异具有统计学意义(P<0.05)。结论:采用血液灌流联合血液透析治疗药物性肝损害患者时,可降低患者胆红素,改善肝功能。
Objective: To investigate the clinical effect of hemoperfusion combined with hemodialysis in the treatment of drug-induced liver damage. Methods: Seventy-six patients with drug-induced liver damage were selected and randomly divided into experimental group and control group. The bilirubin and liver function were compared between the two groups before and after treatment. Results: Before treatment, there was no significant difference in bilirubin and liver function between the two groups (P> 0.05). After treatment, the bilirubin and liver function in the experimental group were higher than those in the control group P <0.05). Conclusion: When hemoperfusion combined with hemodialysis is used to treat patients with drug-induced liver injury, bilirubin can be decreased and liver function improved.