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目的探讨腺瘤样瘤的组织起源。方法应用免疫组化ＳＰ法检测２３例附睾腺瘤样瘤中Ｖｉｍｅｎｔｉｎ和上皮膜抗原（ＥＭＡ）的表达情况。结果本组瘤细胞均表达Ｖｉｍｅｎｔｉｎ，ＥＭＡ除１例阴性表达外、余均阳性表达，说明该肿瘤具有向上皮和间叶双向分化的能力。结论支持腺瘤样瘤可能起源于胚胎残存的Ｍüｌｅｒｉａｎ间叶成分的假说。
Objective To investigate the histological origin of adenomatoid tumors. Methods Immunohistochemical SP method was used to detect the expression of Vimentin and epithelial membrane antigen (EMA) in 23 cases of epididymal adenomatoid tumors. Results Vimentin was expressed in tumor cells in this group. In addition to the negative expression of EMA in one case, the expression of EMA was positive, indicating that the tumor had the ability to bidirectionally differentiate into the epidermis and mesenchymal. Conclusions The hypothesis that adenomatoid tumors may originate from the remaining Mülerian mesenchymal components of the embryo.