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二芳基碘鎓盐属于有机高价碘化合物,具有无毒、反应条件温和以及良好的选择性等优点,在有机合成中具有重要地位,受到广大化学工作者的关注。近年来,利用二芳基碘鎓盐在金属催化下进行的芳基化反应为一些难以合成的杂环化合物的合成提供了简便、高效的方法;同时,二芳基碘鎓盐在无催化剂下进行的芳基化反应,为C—C偶联反应开辟了新的绿色合成路线。本文综述了近年来二芳基碘鎓盐在有机合成中促进芳基化反应的最新进展,着重介绍了利用二芳基碘鎓盐作为芳基化试剂与有机金属试剂、烯烃和炔烃类以及杂环化合物进行芳基化反应的研究;总结了二芳基碘鎓盐与杂环化合物反应中钯催化和铜催化下芳基化反应的机理,最后对二芳基碘鎓盐在今后有机合成中的应用作出了展望。
Diaryliodonium salts belong to organic hypervalent iodine compounds, with non-toxic, mild reaction conditions and good selectivity, etc., has an important position in organic synthesis, by the majority of chemists attention. In recent years, the arylation reaction using diaryliodonium salts under metal catalysis has provided a simple and efficient method for the synthesis of heterocyclic compounds that are difficult to synthesize. Meanwhile, the diaryliodonium salts are used in the absence of catalyst The arylation reaction for the C-C coupling reaction has opened up a new green synthetic route. This review summarizes the recent progress of diaryliodonium salts in promoting arylation in organic synthesis, and highlights the use of diaryliodonium salts as arylating agents with organometallic reagents, olefins and alkynes and Heterocyclic compounds for arylation reaction; summarizes the reaction of diaryliodonium salt and heterocyclic compounds palladium catalytic and copper-catalyzed arylation reaction mechanism, and finally on the diaryliodonium salt in the future organic synthesis In the application of the outlook.