自1957年JacobsoOn及其同事证实了红细胞生成素的肾性起源以来,人们一直在设想慢性肾脏疾病之贫血至少部分是由于缺乏这种肾性激素所引起。如果能给以足够大量的红细胞生成索,贫血则可能被纠正。分子生物学现已提供了这样的剂量。Eschbach、Winearls及其同事最近已经提供了长期血透的贫血病人重组体红细胞生成素治疗作用 Since JacobsoOn and colleagues confirmed the renal origin of erythropoietin in 1957, it has long been envisioned that anemia in chronic kidney disease is caused at least in part by the lack of such kidney hormones. Anemia can be corrected if enough red blood cells are produced. Molecular biology has now provided such a dose. Eschbach, Winearls and colleagues recently provided the therapeutic effect of recombinant erythropoietin on patients with long-term hemodialysis anemia