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早在20世纪50年代研究已发现,在应力作用下生物骨表面的电荷会发生重排,产生电信号,具有压电效应。骨的这种压电特性提示,如果将电活性成分加入移植材料,可能会有助于提高骨的形成速度和质量。随着科学技术的发展以及研究的深入,工业用压电材料已被作为骨替代材料引入医疗领域,模仿生成骨表面电荷从而促进骨愈合。本文就骨压电效应以及压电材料促进成骨机制等方面做简要说明,并对骨组织植入用压电材料的研究与发展前景做一综述。
As early as the 1950s, studies have found that under the action of stress, the charges on the surface of the biological bone will be rearranged to generate electrical signals with a piezoelectric effect. This piezoelectric nature of the bone suggests that adding electrically active ingredients to the graft material may help increase the rate and quality of bone formation. With the development of science and technology and further research, piezoelectric materials for industrial use have been introduced into the medical field as bone substitute materials to mimic the bone surface charges and promote bone healing. In this paper, the piezoelectric effect and piezoelectric materials to promote osteogenesis and other aspects of a brief description of the piezoelectric materials and bone implant implants for the research and development prospects are reviewed.