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胰高血糖素样肽-1(GLP-1)具有降低血糖、改善β细胞功能并阻止其凋亡、延缓胃排空和保护心血管等多种功效,其用于糖尿病治疗的应用研究是近期临床内分泌领域的关注焦点。本文简要综述GLP-1的生理功能以及GLP-1受体激动剂的临床应用进展。
Glucagon-like peptide-1 (GLP-1) has many functions such as lowering blood sugar, improving β-cell function and preventing apoptosis, delaying gastric emptying and protecting cardiovascular. Its application in the treatment of diabetes is recently Clinical focus of the field of endocrine focus. This article briefly reviewed the physiological function of GLP-1 and the clinical application of GLP-1 receptor agonist.