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目的研究胃癌组织中nm23、MMP-2的表达与SCT关于胃癌淋巴结转移的关系。方法用免疫组化方法检测胃癌组织中nm23、MMP-2的表达情况,并分析其表达与胃癌淋巴结转移的关系。结果 67例胃癌组织中,nm23和MMP-2表达阳性率分别为41.8%(28/67)和73.1%(49/67)。胃癌组织中nm23、MMP-2的表达与淋巴结转移密切相关。结论胃癌组织中nm23、MMP-2的表达与SCT征象胃癌淋巴结转移密切相关。
Objective To study the relationship between the expression of nm23 and MMP-2 in gastric carcinoma and the lymph node metastasis of gastric cancer. Methods The expression of nm23 and MMP-2 in gastric cancer tissues was detected by immunohistochemistry. The relationship between the expression of nm23 and MMP-2 and the lymph node metastasis of gastric cancer was analyzed. Results The positive rates of nm23 and MMP-2 in 67 cases of gastric carcinoma were 41.8% (28/67) and 73.1% (49/67), respectively. The expression of nm23 and MMP-2 in gastric cancer is closely related to lymph node metastasis. Conclusion The expression of nm23 and MMP-2 in gastric cancer is closely related to the lymph node metastasis of SCT.