血浆置换已被作为对包括狼疮性肾炎在内的许多免疫介导疾病的有效辅助治疗,一般认为疗效与循环免疫复合物(CIC)的检出及在血浆置换时被清除有关。作者报告1例进展性广泛性血管炎的 SLE 患者,尽管没有检出 CIC,血浆置换却取得了显著的改善。 Plasma exchange has been used as a potent adjuvant therapy for many immune-mediated diseases, including lupus nephritis. It is generally accepted that efficacy is associated with the detection of circulating immune complexes (CICs) and their clearance during plasma exchange. The authors report a significant improvement in plasma exchange in 1 SLE patients with progressive extensive vasculitis, although no CIC was detected.