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目的:比较分析2011-2015年南宁市互助献血与自愿无偿献血者输血相关传染病检测结果之间的差异,为采供血机构制定有效措施提供统计学支持。方法:对南宁市2011-2015年无偿献血者588 194人次(自愿无偿献血者375 023人次,互助献血者213 171人次)的血液标本运用酶联免疫吸附试验(ELISA)检测乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、人类免疫缺陷病毒抗体(抗-HIV)、梅毒螺旋体特异性抗体(抗-TP)并进行统计分析。结果:2011-2015年互助献血人数呈逐年增长的趋势(P<0.05);尽管互助献者HBsAg(P<0.05)和抗-TP(P<0.01)的阳性率呈下降的趋势,但互助总的阳性率(1.90%)显著高于自愿无偿献血总阳性率(1.11%)(P<0.01),OR=1.709,95%CI=1.640~1.780。结论:过高的互助献血比率,其潜在的输血风险性高于来源自愿无偿献血,采供血机构应该依法推动无偿献血工作,加强互助献血管理,严格控制互助献血启动的条件、标准和范围,不断降低互助献血率。
OBJECTIVE: To compare and analyze the difference between the blood transfusion-related infectious diseases of blood donation and volunteer blood donation in Nanning from 2011 to 2015 so as to provide statistical support for the effective measures of blood collection and blood donation agencies. Methods: The blood samples of 588 194 volunteers (375 023 voluntary blood donors and 213 171 mutual aid blood donors) from 2011 to 2015 in Nanning were detected by enzyme-linked immunosorbent assay (ELISA) for the detection of hepatitis B virus surface antigen (HBsAg), Hepatitis C virus (anti-HCV), human immunodeficiency virus (anti-HIV), and Treponema pallidum specific antibodies (anti-TP) Results: The number of reciprocal blood donation increased from 2011 to 2015 (P <0.05). Although the positive rate of HBsAg (P <0.05) and anti-TP (P <0.01) (1.90%) was significantly higher than the total positive rate of volunteer blood donation (1.11%) (P <0.01), OR = 1.709, 95% CI = 1.640-1.780. Conclusion: Too much blood donation ratio has the potential risk of blood transfusion higher than voluntary voluntary blood donation. Blood collection agencies should promote blood donation according to law, strengthen mutual blood donation management and strictly control the conditions, standards and scope of mutual aid blood donation Reduce the mutual donation rate.