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目的探讨肺移植术后胃食管反流病预防和治疗的经验。方法终末期肺病患者8例,1例行单肺移植,7例行双肺移植。所有患者术后给予机械通气、液体负平衡、抗感染和抗排斥等治疗。部分患者给予抗胃食管反流病治疗。结果受者早期存活5例,死亡3例。8例患者中5例未行胃食管反流病预防性治疗,其中2例诊断误吸,经抗反流治疗后明显好转;3例常规行胃食管反流病的预防治疗,未见明显误吸,且恢复良好。结论肺移植是治疗终末期肺病的有效方法。胃食管反流病在肺移植术后常见,防治胃食管反流病对于预防术后肺部并发症有重要作用。
Objective To investigate the prevention and treatment of gastroesophageal reflux disease after lung transplantation. Methods 8 cases of end-stage lung disease, one case of single lung transplantation, 7 cases of double lung transplantation. All patients were given mechanical ventilation, fluid negative balance, anti-infective and anti-rejection treatment. Some patients given anti-gastroesophageal reflux disease treatment. Results The recipients survived in 5 cases and died in 3 cases. Five of the 8 patients did not receive prophylactic treatment of gastroesophageal reflux disease, of which 2 were diagnosed as aspiration and were significantly improved after anti-reflux treatment. The prevention and treatment of 3 cases with conventional gastroesophageal reflux disease showed no obvious error Suck, and recover well. Conclusion Lung transplantation is an effective method for the treatment of end-stage lung disease. Gastroesophageal reflux disease common after lung transplantation, prevention and treatment of gastroesophageal reflux disease for the prevention of postoperative pulmonary complications have an important role.