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目的通过小柴胡汤加减而成的柴胡生血方促进骨髓抑制小鼠造血相关指标改善的实验研究,探讨“少阳春生之气”理论对化生气血的临床指导作用。方法制造小鼠骨髓抑制模型后分别用复方阿胶浆和柴胡生血方灌胃给药,测定给药各组对小鼠WBC、RBC、IL-6各项指标的影响。结果柴胡生血方汤组对WBC、RBC、IL-6含量的回升显示出了作用。结论以小柴胡汤加减的柴胡生血方有促进骨髓抑制小鼠造血功能恢复的作用,说明李东垣“少阳春生之气”理论对治疗白血病有临床指导意义。
Objective To study the effect of Chaihu Shengxue Fang added and subtracted from Xiao Chai Hu Tang on the improvement of hematopoiesis-related markers in myelosuppressed mice, and to explore the clinical guiding role of “Shaoyang Chu Qi Qi” theory in the production of qi blood. Methods After the mouse model of myelosuppression was established, the mice were administered with compound gelatin and Chaihu Shengxue respectively, and the effects of each group on the indexes of WBC, RBC and IL-6 in mice were determined. Results Chaihu Shengxuefangtang group showed an effect on the recovery of WBC, RBC and IL-6. Conclusions Chaihu Shengxue decoction with Xiaochaihu decoction can promote the recovery of hematopoietic function in myelosuppressed mice, indicating that Li Dongyuan ’s theory of “Shaoyang Chunsheng Qi ” has clinical significance in the treatment of leukemia.