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自从CD4(T4)抗原被鉴定为人免疫缺陷病毒(HlV-1)细胞表面受体的一种基本成份后,它就成为广泛研究的任何被膜病毒受体之一。现已有5篇论文表明,可溶型CD4抗原(sCD4)能阻断病毒的传染性。美国正计划将sCD4作为抗病毒剂的临床试验。
Since CD4 (T4) antigen has been identified as an essential component of the human cell surface receptor of human immunodeficiency virus (HlV-1), it has become one of the most widely studied receptors for any of the enveloping viruses. Five papers have now been shown that soluble CD4 antigen (sCD4) blocks the virus’s infectivity. The United States is planning to use sCD4 as an antiviral clinical trial.