目的:探讨高压氧(HBO)综合治疗带状疱疹的临床疗效。方法:选取2018年1月至2019年12月就诊于郑州市第二人民医院皮肤科带状疱疹患者72例，按随机数字表法分为HBO组和对照组，每组36例。对照组给予阿昔洛韦等常规治疗，HBO组在常规治疗基础上给予HBO治疗，观察2组患者皮损改善情况，并进行疼痛强度评分(NRS)及临床疗效评价。治疗后3个月随访，统计带状疱疹后神经痛(PHN)的发生情况。结果:治疗后HBO组止疱时间、水疱开始结痂时间、水疱完全结痂时间均短于对照组，差异均有统计学意义(n P<0.05)；2组患者NRS评分均低于治疗前，且HBO组患者治疗后NRS低于对照组，差异均有统计学意义(n P<0.05)；HBO组治疗总有效率(91.67%)明显高于对照组(83.33%)，差异有统计学意义(n χ2＝4.31，n P＝0.04)。HBO组患者PHN发生3例(8.33%)，对照组患者PHN发生7例(19.44%)，差异有统计学意义(n P<0.05)。n 结论:HBO综合治疗带状疱疹具有较好的临床疗效，值得临床推广应用。“,”Objective:To observe the clinical effect of the treatment combined with hyperbaric oxygen (HBO) on patients with herpes zoster.Methods:A total of 72 patients with herpes zoster treated in the Department of Dermatology of Zhengzhou Second Hospital from January 2018 to December 2019 were selected and divided into HBO group and control group by random number table method, with 36 patients in each group. The control group received acyclovir and other conventional treatments, while the HBO group received HBO on the basis of the treatments of the control group. The improvement of the skin lesions, scores of numeric rating scales (NRS) on pain, and efficacy of the two groups were observed and evaluated after treatment. After a 3-month follow-up, the occurrence of postherpetic neuralgia (PHN) was statistically analyzed.Results:The time of blistering relieving, incrustation, and complete incrustation of the HBO group were all lower than those of the control group with statistically significant difference (n P<0.05). The NRS scores of both groups were all lower than those before treatment with significantly statistical difference (n P<0.01); and the NRS scores of the HBO group were significantly lower than those of the control group after treatment (n P<0.05). The total effective rate of the HBO group (91.67%) was significantly higher than that of the control group (83.33%). The difference was statistically significant (n χ2=4.31, n P=0.04). After treatment, 3 cases of PHN occurred in the HBO group, while 7 cases in the control group; the PHN incidence of the HBO group was lower than that of the control group with significantly statistical difference (n P<0.05).n Conclusion:In treating herpes zoster, the treatment combined with HBO can achieve a satisfactory therapeutic effect, which is worthy of popularization and application in clinic.