论文部分内容阅读
目的比较血清抗体和快速尿素酶检测幽门螺杆菌(Hp)感染的灵敏度及特异性。方法选取2014年5月至2015年12月该院门诊及住院患者100例,行胃镜检查时在内镜指导下活检胃窦黏膜组织1块立即进行快速尿素酶检查,随后进行血清抗体检测。以病理组织学检查结果阳性作为对照,比较2种方法检测Hp感染的灵敏度、特异性。结果血清抗体检查Hp阳性率明显高于快速尿素酶,血清抗体检测Hp感染的灵敏度明显高于快速尿素酶,差异均有统计学意义(P<0.05)。血清抗体检测Hp感染的特异性与快速尿素酶相当。结论血清抗体检测Hp感染的灵敏度较高,特异性与快速尿素酶相当,是一种普查Hp感染的较理想的检测方法,但快速尿素酶检测费用低、费时少,适合经济水平低及门诊患者的检测。
Objective To compare the sensitivity and specificity of serum antibodies and rapid urease in the detection of Helicobacter pylori (Hp) infection. Methods From May 2014 to December 2015, 100 outpatients and inpatients from May 2014 to December 2015 were enrolled in this study. One hundred patients with gastric mucosa under biopsy under endoscopy under endoscopy were selected for rapid urease test immediately. Serum antibodies were detected subsequently. Histopathological examination results as a positive control, the two methods to detect Hp infection sensitivity and specificity. Results The positive rate of Hp in serum antibody was significantly higher than that in rapid urease. The sensitivity of serum antibody to detect Hp infection was significantly higher than that of rapid urease, the difference was statistically significant (P <0.05). The specificity of serum antibody to detect Hp infection is comparable to that of rapid urease. Conclusions Serum antibody is more sensitive and specific than rapid urease in detection of Hp infection. It is an ideal method for screening Hp infection. However, the rapid urease test is less costly and time-consuming, and is suitable for low-cost patients and outpatients The test.