我国约有50%育龄妇女采用宫内节育器(IUD)避孕,失败率10～15%,以出血取环为主要原因。为提高IUD的使用效果,国内外对带器子宫的微环境改变进行了大量的实验和临床研究。国外早在1966年就发表了有关文章,国内自1980年以来,在这方面也有零星报道。现就带器妇女子宫内膜形态学变化作一概述。研究证实,IUD能有效地抗生育,不是简单的机械作用,而是与IUD引起的子宫微环境一系列生理、生化和形态学变化有关。一、IUD对子宫内膜发育的影响不少学者发现带器子宫内膜的发育落后于周期,即发育延迟。Czernobilsky等报告33.5%子 About 50% of women of childbearing age in our country use intrauterine device (IUD) contraception, the failure rate of 10 to 15%, bleeding to take the loop as the main reason. In order to improve the effect of IUD, a large number of experimental and clinical researches have been carried out on the microenvironmental changes of uterus with and without uterus at home and abroad. As early as 1966, foreign countries published relevant articles. Since 1980, there have also been sporadic reports in this area in China. Now with the changes of women with endometrial morphology to make an overview. Studies have shown that IUD can effectively resist childbirth, not a simple mechanical action, but rather a series of physiological, biochemical and morphological changes related to IUD-induced uterine microenvironment. First, the impact of IUD on endometrial development Many scholars found that the development of the device with the endometrium lags behind the cycle, that is, delayed development. Czernobilsky et al reported 33.5% children