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目的了解国内凝固酶阴性葡萄球菌(CNS)医院感染及耐药现状。方法CNS鉴定及药敏试验均采用法国生物梅里埃公司生产的VITEK32型CC4系列GPI及GPS卡进行检测。结果分离到表皮、溶血、里昂、模仿、腐生、耳、头状、施氏、木糖葡萄球菌等CNS共9种,其中表皮葡萄球菌居首位(50.0%)。CNS对青霉素耐药率为95.5%,耐甲氧西林CNS(MRCNS)占53.8%,且呈多重耐药状态。尚未发现耐万古霉素葡萄球菌。结论CNS医院感染率及耐药性呈增高趋势,应予重视。
Objective To understand the status of nosocomial infection and drug resistance of coagulase-negative staphylococci (CNS) in China. Methods CNS identification and drug susceptibility tests were performed using the VITEK32 CC4 series GPI and GPS card produced by the French company Bio Merrill. Results Nine kinds of CNS including epidermis, hemolysis, Lyon, imitation, saprophytic, ear, head, Shigella spp. And Staphylococcus xylosus were isolated. Staphylococcus epidermidis ranked first (50.0%). The drug resistance rate of CNS to penicillin was 95.5% and that of methicillin-resistant CNS (MRCNS) was 53.8%. The drug resistance was multi-drug resistant. No vancomycin-resistant staphylococci have been found. Conclusion The infection rate and drug resistance of CNS hospital are on the rise and should be paid attention to.