建立了格列喹酮血药浓度的测定方法。该法使用ＳｐｈｅｒｉｓｏｒｂＣ１８色谱柱，以乙腈－水（６５３５）为流动相，流速为１．０ｍｌ／ｍｉｎ，检测波长为３１０ｎｍ，灵敏度为０．００１ＡＵＦＳ。线性范围为５０～２０００ｎｇ／ｍｌ，方法回收率为９５％以上，日内、日间误差小于７．０％。 The determination of gliquidone concentration was established. The method uses SpherisorbC18 ​​column with acetonitrile-water (6535) as the mobile phase at a flow rate of 1.0 ml / min with a detection wavelength of 310 nm and a sensitivity of 0.001 AUFS. Linear range of 50 ~ 2000ng / ml, the method recovery rate of 95%, day, daytime error of less than 7.0%.