皮肤瘙痒是尿毒症患者常见的并发症之一,其临床发生率高达50%～75%,而其中有37%的病人表现为令人心烦的皮肤瘙痒,严重影响患者生活质量,单纯采用西医局部用药或口服抗瘙痒药物通常疗效不佳,治疗上颇为棘手[1]。近年来,随着血液滤过及血液灌流在临床上的广泛应用,尿毒症患者合并顽固性皮肤瘙痒有所减少,但仍然有部分病人症状改善不明显,为此,我们于2007年2月～2009年2月,对我科收治的68例尿毒症维持性血液透析 Skin itching is one of the common complication of uremia patients, the clinical incidence as high as 50% to 75%, of which 37% of patients showed upset the skin itching, seriously affecting the quality of life of patients, the simple use of Western medicine Medication or oral anti-pruritus drugs usually poor efficacy, the treatment is quite tricky [1]. In recent years, with the extensive application of hemofiltration and hemoperfusion in clinic, patients with uremia with stubborn pruritus have been reduced, but there is still no obvious improvement in some patients. Therefore, in February 2007 ~ February 2009, 68 cases of uremic maintenance hemodialysis admitted to our department