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目的:探讨都哈理论(DOHAD)干预在孕妇孕期营养指导中预防巨大儿和低体重儿出生率的应用及临床效果。方法:按自愿原则抽取足月单胎活产孕妇1100例,随机分为实验组和对照组各550例,对照组给予常规孕期营养指导,实验组在此基础上给予DOHAD理论孕期营养指导。比较两组孕妇平均每周体重增加情况、巨大儿与低体重儿出生率。结果:实验组平均每周体重增加情况、巨大儿与低体重儿出生率明显低于对照组(P<0.05)。结论:在DOHAD理论指导下,通过孕期营养干预,可控制孕妇平均每周体重增加,降低巨大儿和低体重儿的出生率。
Objective: To investigate the application and clinical effects of DOHAD intervention in the prevention of maternal and neonatal birth rates in pregnant women during pregnancy. Methods: One hundred and ten pregnant women with full-term single live birth were randomly divided into experimental group and control group with 550 cases each. The control group was given nutrition guidance during regular pregnancy. On the basis of the experimental group, DOHAD theory was given nutritional guidance during pregnancy. Compare the average weight gain of pregnant women in two groups, the birth rate of huge children and low birth weight children. Results: The average weekly weight gain in experimental group was significantly lower than that in control group (P <0.05). Conclusion: Under the guidance of DOHAD theory, pregnant women can control the average weekly weight gain and reduce the birth rate of macrosomia and low birth weight infants through nutritional intervention during pregnancy.