金刚烷胺系临床常用药,当用量偏大时,可引起不良反应,但引起严重精神障碍者少见,今有1例报道如下: 病例介绍: 患者,女,45岁,军医。因哭闹不安,情感兴奋已10小时于1975年6月10日入院。4天前即6月6日开始全身不适,发烧,体温38℃,食欲减退。7日就诊于门诊所,口服金刚烷胺0.2gm,2/日。8日全身症状减轻,自觉服药有效,又自动加服共服总量1gm克。9日体温正常,照常上班,当夜失眠10日午睡时,情绪低落,哭了2个小时,下午仍去上班,其他同志对她说:“你怎么把眼睛都哭肿 Amantadine drugs commonly used in clinical practice, when the amount is too large, can cause adverse reactions, but caused by severe mental disorders are rare, one case reported as follows: Case description: The patient, female, 45 years old, military doctor. Due to crying uneasiness, emotional excitement has been 10 hours in June 10, 1975 admission. 4 days ago that June 6 began to malaise, fever, body temperature 38 ℃, loss of appetite. Visit the clinic on the 7th, oral amantadine 0.2gm, 2 / day. Symptoms on the 8th to alleviate, consciously take medicine effective, and automatically add service total serving 1gm grams. On the 9th, the body temperature was normal and went to work as usual. When it was napped on the 10th of the night for insomnia, she was depressed and cried for 2 hours. She still went to work in the afternoon. Other comrades said to her: