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血小板活性增加是心、脑血管疾病的一个危险因子。业已证实电子计算机体层摄影(CT)对鉴别皮质梗塞与脑深部梗塞是有效的。作者研究脑血栓时血小板的凝集性,结合CT和脑血管造影判断血小板凝集性与血管狭窄程度及脑梗塞类型之间的关系。共观察48例,根据脑血管造影所见分为两组:颅内大动脉管腔狭窄超过75％为严重狭窄组,共25例,男19、女6例,平均年龄50岁;动脉管腔狭窄在75％以下或无狭窄者为轻度狭窄组,共23例,男15、女8例,平均年龄58岁。大部分病人的血压正常。在脑血栓急性期后(发病后2周以上),血小板凝集性增高;严重血管狭窄或闭塞组25例中血小板凝集性增高占5例(20％);CT检查常能发现皮质或大脑深部病变,而血管轻度狭窄的23例血小板凝集性增高者达13例(57％),此组多数病人有顽固性高血压与深部小梗塞。
Increased platelet activity is a risk factor for heart and cerebrovascular disease. It has been demonstrated that computed tomography (CT) is effective in identifying cortical infarcts and deep brain infarcts. The authors studied platelet aggregation in cerebral thrombosis, combined with CT and cerebral angiography to determine the relationship between platelet aggregation and vascular stenosis and cerebral infarction type. A total of 48 cases were observed according to cerebral angiography were divided into two groups: more than 75% of the stenosis of intracranial aortic stenosis was severe stenosis group, a total of 25 cases, 19 males and 6 females, mean age 50 years; arterial stenosis In less than 75% or no stenosis were mild stenosis group, a total of 23 cases, 15 males and 8 females, mean age 58 years. Most patients have normal blood pressure. In the acute phase of cerebral thrombosis (more than 2 weeks after onset), platelet aggregation increased; 25 cases of severe vascular stenosis or occlusion group increased platelet aggregation accounted for 5 cases (20%); CT examination can often find cortical or deep brain lesions , And thirteen patients (57%) had increased platelet aggregation in 23 cases with mild stenosis. Most patients in this group had refractory hypertension and deep small infarction.