Application of dual color fluorescence in situ hybridization (D—FISH) to the diagnosis of a 49,XXXXY

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Objective:To study the technique of D-FISH and its application in the diagnosis of a 49.XXXXY chromosomal abnormality.Methods:Biotin-labeled alpha satellite X chromosome DNA(pBamX7) probe and digoxi-genin-labeled Y chromosome long arm terminal repetitive
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