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目的：观察SLE患者血清可溶性IL—2R水平及其临床意义。方法：应用双抗体夹心法对系统性红斑狼疮（SLE）患者治疗前、后及正常人血清可溶性白细胞介素2受体（SIL—2R）水平进行了检测。结果：SLE患者血清sIL—2R水平较正常人升高；应用肾上腺糖皮质激素治疗有效后血清sIL—2R水平明显下降，无效者则无降低；SLE患者血清sIL—2R水平与疾病活动指数呈正相关。提示：血清sIL—2R水平可作为判定疾病活动性的指标及疗效判定指标。
Objective: To observe the serum soluble IL-2R level in patients with SLE and its clinical significance. Methods: Serum soluble interleukin-2 receptor (SIL-2R) levels in patients with systemic lupus erythematosus (SLE) before and after treatment were measured by double antibody sandwich method. Results: The level of serum sIL-2R in patients with SLE was higher than that in healthy people. Serum sIL-2R level was decreased significantly after glucocorticoid treatment was effective, but was not reduced in patients with SLE. The level of sIL-2R in SLE patients was positively correlated with disease activity index . Tip: serum sIL-2R levels can be used as indicators to determine disease activity and efficacy indicators.