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(一)在氯醛糖和氨基甲酸乙酯麻醉的兔或未麻醉的箭毒化兔,右心房内输液(输入量为8—10毫升/公斤,输入速度为0.5—1.0毫升/秒),可规律地引起心率减慢和动脉血压下降。(二)右心房输液引起的心率变化,在切断两对缓冲神经和迷走神经后并不消失,说明此种输液效应并非反射作用。(三)经颈外静脉向右心房内引入一小气囊,以不同压力扩张后,也可导致心率减慢。此时气囊内压值与心率变化之间的关系不是完全呈直线式的。切断迷走神经后,效应仍存在;且此效应也不是由于气囊扩张阻断血液回流所致。(四)以奴佛卡因溶液阻断窦房结区后,右心房输液不再引起心率减慢。全身低温或选择性心脏低温(26—28℃)后,大多数实验中的心率在输液后不再变慢,由此说明右心房内输液对心率的影响是刺激直接作用于窦房结而改变其机能活动的结果。(五)在我们的实验条件下,从兔身上不能证示有 Bainbridge 反射的存在。
(A) In a chloralose and urethane anesthetized rabbit or a non-anesthetized poisoned rabbit, a right atrial infusion (8-10 ml / kg input, 0.5-1.0 ml / sec infusion rate) Regularly cause slow heart rate and arterial blood pressure. (B) changes in heart rate caused by right atrial infusion, in the cut off after two pairs of nerve and vagus nerve does not disappear, indicating that such infusion effect is not a reflection effect. (C) the introduction of a small balloon through the external jugular vein to the right atrium, with different pressures, can also lead to slow heart rate. At this point the relationship between balloon pressure and heart rate changes is not completely rectilinear. After cutting off the vagus nerve, the effect still exists; and this effect is not due to the expansion of the balloon blocking blood reflux. (D) of Novocaine solution to block the sinoatrial node area, the right atrial infusion does not cause heart rate slowed down. After systemic hypothermia or selective heart hypothermia (26-28 ° C), the heart rate in most of the experiments did not slow down after infusion, indicating that the effect of right atrial infusion on heart rate was stimulated to act directly on the sinus node The result of its functional activity. (E) Under our experimental conditions, the presence of Bainbridge reflexes can not be demonstrated from the rabbit.