近年来,人们经多方努力筛选出某些可降低肿瘤发生率韵有效化合物。应运而出现的已有维甲酸类化合物、抗氧化剂、花生四烯酸(arachidonic acid)代谢抑制剂等。它们对化学诱癌实验动物均显示颇为有效的致癌抑制作用。本文作者报道一类新的化学预防化合物(tricyclodecan-9-yl-xanthogenate,简称 D609)具有抗病毒与抗肿瘤作用,是一种黄原酸盐化合物。实验所用动物为7周龄的雌性 NMRI 小鼠,每组20只。采取经典起始-促进(initiation- In recent years, people have tried hard to screen out certain effective compounds that can reduce the incidence of tumors. There have been retinoids, antioxidants, arachidonic acid metabolism inhibitors, and the like that have emerged. They showed quite effective carcinogenic inhibition on chemically induced cancer animals. The authors report that a novel class of chemopreventive compounds (tricyclodecan-9-yl-xanthogenate, abbreviated as D609) has antiviral and antitumor effects and is a xanthogenate compound. The experimental animals were 7-week-old female NMRI mice, 20 in each group. Take the classic start- promotion (initiation-