小鼠的继发性细粒棘球蚴囊在含甲苯达唑阿苯达唑或阿苯达唑亚枫1及10μg/ml的培养液中培养l～7d时,囊壁所含各药物的量相近,但生发层的受损以甲苯达唑组较重,次为阿苯达唑亚砜和阿苯达唑组。感染小鼠ig上述3种苯并咪唑类化合物的等效剂量1～14d后24h,囊壁的药物含量甚低,但生发层的损害仍以甲苯达唑组的较重,并认为阿苯达唑亚矾是阿苯达唑的有效代谢物。 Mouse secondary granule hydatid cyst in containing benzalkonium albendazole or albendazole acephate 1 and 10μg / ml of culture medium l ~ 7d, the wall of the drug contained in each drug However, the damage of the germinal layer was heavier in the mebendazole group, followed by albendazole sulfoxide and albendazole group. Infected mice ig the three benzimidazoles equivalent dose 1 ~ 14d after 24h, the wall of the drug content is very low, but the germinal layer damage is still mebendazole group heavier and that albendazole Azathione is an effective metabolite of albendazole.